About NAD+
NAD+ is the dinucleotide coenzyme required for sirtuin activation, DNA repair, and oxidative phosphorylation. Subcutaneous NAD+ at 100 mg every 3 days produced zero serious adverse events in the 2022 NIA pilot.
Reported benefits
- Restores plasma NAD+ within 6 hours (IV) or 24 hours (SC)
- Drives sirtuin and PARP enzyme activity
- Zero serious adverse events in NIA pilot
Research citations
- Grant et al. 2019 - Frontiers in Aging Neuroscience
- Martens et al. 2018 - Nature Communications
How NAD+ fits the category
NAD+ sits inside the NAD+ Peptide Guide category. For the full ranking and head-to-head comparisons, read NAD+ Peptide Guide.